email: brian.galletta@nih.gov
phone: (301)496-4008
–
CURRENT POSITION
Staff Scientist in the Rusan Lab
HISTORY
1997 – B.S., The Pennsylvania State University (Biology)
2004 – Ph.D., The Pennsylvania State University (Advisor: Dr. Susan Abmayr)
2004 – 2009 – Postdoctoral fellow, Washington University School of Medicine (Advisor: Dr. John Cooper)
2009 – 2011 – Research Assistant Professor, Washington University School of Medicine
2011 – 2018 – Research Fellow, CBPC, NHLBI, NIH
PUBLICATIONS (PubMed)
20. McLamarrah TA, Buster DW, Galletta BJ, Boese CJ, Ryniawec JM, Hollingsworth NA, Byrnes AE, Brownlee CW, Slep KC, Rusan NM, Rogers GC. An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly. Journal of Cell Biology, 217(4):1217-1231
19. Galletta B.J., Fagerstrom, C.J., Schoborg, T.A., McLamarrah, T.A., Ryniawec, J.M, Buster, D.W., Slep, K.C., Rogers G.C., Rusan, N.M.. A detailed centrosome interactome provides insight into organelle assembly and human disease. Nature Communications, 7:12476
18. Galletta B.J., Jacobs K.C., Fagerstrom C.J., and Rusan, N.M. Asterless is required for centriole length control and sperm development. Journal of Cell Biology, 23;213(4):435-50
17. Wang, X., Galletta, B.J., Cooper J.A. and, Carlsson A.E. (2016) Actin-Regulator Feedback Interactions during Endocytosis. Biophys. J. 110(6):1430-43
16. Plevock, K.M., Galletta B.J., Slep K.C. and Rusan, N.M. (2015) Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells. PLoS One. 10:e0144174
15. Galletta BJ#, Rusan NM. (2015) A yeast two-hybrid approach for probing protein-protein interactions at the centrosome. Methods in Cell Biology, 129:251-77. #corresponding author
14. Lerit DA, Jordan HA, Poulton JS, Fagerstrom CJ, Galletta BJ, Peifer M, Rusan NM. (2015) Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function. Journal of Cell Biology, 210(1):79-97.
13. Klebba JE*, Galletta BJ*, Nye J, Plevock KM, Buster DW, Hollingsworth NA, Slep KC, Rusan NM#, Rogers GC#. (2015) Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability. Journal of Cell Biology, 16;208(4):401-14. *co-first authors, #co-corresponding authors
12. Galletta BJ*, Guillen RX*, Fagerstrom CJ, Brownlee CW, Lerit DA, Megraw TL, Rogers GC, Rusan NM. (2014) Drosophila Pericentrin requires interaction with Calmodulin for its function at centrosomes and neuronal basal bodies, but not at sperm basal bodies. Mol Biol Cell. 2014 Jul 16. *co-first author
11. Galletta BJ, Carlsson AE, Cooper JA. (2012) Molecular analysis of Arp2/3 complex activation in cells. Biophys J. 103 (10):2145-56.
10. Mooren OL*, Galletta BJ*, Cooper JA. (2012) Roles for actin assembly in endocytosis. Annu Rev Biochem. 81:661-86. *co-first author
9. Galletta BJ, Mooren OL, Cooper JA. (2010) Actin dynamics and endocytosis in yeast and mammals. Curr Opin Biotechnol. 21(5):604-10.
8. Lin MC, Galletta BJ, Sept D, Cooper JA. (2010) Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo. J Cell Sci. 123(Pt 8):1329-42.
7. Galletta BJ, Cooper JA. (2009) Actin and endocytosis: mechanisms and phylogeny. Curr Opin Cell Biol. 21(1):20-7.
6. Galletta BJ, Chuang DY, Cooper JA. (2008) Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol. 6(1):e1.
5. Kim K*, Galletta BJ*, Schmidt KO, Chang FS, Blumer KJ, Cooper JA. (2006) Actin-based motility during endocytosis in budding yeast. Mol Biol Cell. 17(3):1354-63. *co-first author
4. Galletta BJ, Chakravarti M, Banerjee R, Abmayr SM. (2004) SNS: Adhesive properties, localization requirements and ectodomain dependence in S2 cells and embryonic myoblasts. Mech Dev. 121(12):1455-68.
3. Abmayr SM, Balagopalan L, Galletta BJ, Hong SJ. (2003) Cell and molecular biology of myoblast fusion. Int Rev Cytol. 225:33-89.
2. Galletta BJ, Niu XP, Erickson MR, Abmayr SM. (1999) Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC. Gene.228(1-2):243-52
1. Erickson MR, Galletta BJ, Abmayr SM. (1999) Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization. J Cell Biol. 138(3):589-603.
OTHER PUBLICATIONS
1. Abmayr, S.M., Balagopalan, L., Galletta, B.J. and Hong, S. (2005) Myogenesis and Muscle Development. In: Comprehensive Molecular Insect Science. (Gilbert, L.I., Iatrou, K., Gill, S.S., eds.). Elsevier, New York. Vol. 2, pp. 1-44.
INVITED SEMINARS
2018 Triangle Cytoskeleton Meeting, ASCB regional meeting, Saxapahaw, NC
2016 The Chicago Cytoskeleton meeting, Chicago, IL.
2014 The 54th annual ASCB meeting, Philadelphia, PA. Special interest group: Positioning the MTOC: A matter of life or death
2014 The 3rd Centrosome and Spindle Pole Body EMBO meeting, Lisbon, Portugal
2014 University of Colorado School of Medicine, Department of Cell and Developmental Biology, Denver, CO
2014 The 1st annual NIH Centrosome and Cilia Guild, Frederick, MD
2014 The 12th annual NHLBI Division of Intramural Research Scientific Retreat, Bethesda, MD
2014 The 55th annual Drosophila Research Conference, San Diego, CA. Workshop: Centrosomes and Cilia in Cell Division and Disease
2010 Gordon Research Conference: Plant and Microbial Cytoskeleton, Andover, NH.
2007 Cold Spring Harbor Laboratory Meeting: Yeast Cell Biology, Cold Spring Harbor, NY
2003 Midwest Regional Developmental Biology Annual Meeting, Kansas City, MO
2002 American Society for Cell Biology Annual Meeting, San Francisco, CA. Special Interest Subgroup: Cell-Cell Fusion
OF NOTE
2019 Best talk award, Staff Scientist category, NHLBI annual retreat
2017-2020 NHLBI Career Transition Award (K22). – $747,000 direct costs
2012 Outstanding Fellow Poster, 10th National Heart Lung and Blood, Department of Intramural Research Scientific Retreat Ocean City, MD
2007 NIH Ruth L. Kirschstein National Research Service Award (F32)